Plantar warts are noncancerous growths that develop on the soles of the feet. They are caused by the human papillomavirus (HPV). While plantar warts are not a serious health threat, they may cause pain and discomfort while walking or standing. Children, adolescents and patients with immune disorders are most frequently affected by plantar warts. Plantar warts are inherently difficult to treat because it is a virus, however freezing with liquid nitrogen (cryotherapy), application of topical medications, laser treatment, and surgical excision are all viable treatment options.